June 13, 2002 The probiotics Lactobacilli and Saccharomyces boulardii were better than placebo in preventing antibiotic-associated diarrhea, according to a meta-analysis of 9 trials reported in the June 8 issue of the British Medical Journal.
“Probiotics have proved useful in preventing diarrhea, but the number of clinical trials is limited and further controlled trials using different probiotics are needed,” write Frederic Barbut and Jean Luc Meynard, from Hôpital Saint-Antoine in Paris, in an accompanying editorial.
“The key measure for preventing antibiotic-associated diarrhea, however, is to limit antibiotic use.”
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