NORTHBROOK, IL — April 9, 2002 — In a recent article published in CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), researchers found that chronic cough due to gastroesophageal reflux disease (GERD) is not always caused by acid. The study showed that intensive medicinal therapy, including intensive acid suppression may fail to improve chronic cough. When this occurs antireflux surgery can eliminate or significantly improve chronic cough due to GERD.
GERD, a clinical condition that affects seven million people in the U.S. alone, is one of the most common causes of chronic cough in all age groups. It occurs when there is a severe reflux of stomach contents into the esophagus, causing certain symptoms and possible damage. Symptoms include heartburn, regurgitation of gastric juice, chest pain, difficulty breathing and chronic cough.
"There is a subgroup of patients with chronic cough whose intragastric or stomach acidity can be completely or nearly completely suppressed with acid therapy yet they can still have their cough due to GERD," said Richard S. Irwin, MD, FCCP, of the University of Massachusetts Medical School Department of Medicine in Worcester, Mass. "What we've found is that chronic cough is caused not only by acid, but by non-acid mediators such as enzymes as well."
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