Patients with non-melancholic depression have enhanced sensitisation to subsequent episodes of depression, Australian researchers say.
Investigators from the University of New South Wales and Prince of Wales Hospital, both in Randwick, say that the sensitisation findings are consistent with earlier research, but the specificity to non-melancholic depression is not.
They explain that debate has been re-ignited concerning the association between stressful life events and depressive subtype. The researchers investigated the relationship between stressful life events, variably defined melancholic/non-melancholic depressive subtypes, and their relationship to such life events compared to first life events with subsequent episodes across the same subtypes.
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