Results of a study published in the November issue of Fertility and Sterility suggest that administration of tibolone in postmenopausal women decreases plasma levels of free fatty acid and rebalances cardiac autonomic nervous activity.
In a randomized, placebo-controlled trial, Dr. Giuseppe Paolisso, of the University of Naples, Italy, and colleagues examined the effects of tibolone on heart rate variability and plasma levels of free fatty acid in 30 postmenopausal women. The patients received 2.5 mg/d tibolone or placebo for 4 months. The team measured variability in heart rate and change in the lipid profile.
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