Human papillomavirus (HPV) infection precedes development of cervical cancer, according to a population-based prospective study published in the Sept. 14 issue of the British Medical Journal. Most cases of HPV infection are transient, but persistent infection, particularly with the same viral type, significantly increases the risk of high-grade lesions.
“We have shown that HPV infection precedes the development of low and high grade squamous intraepithelial lesions and that high risk HPV infection is a good predictor of subsequent high grade lesions in young women,” write Susanne K. Kjaer, from the Institute of Cancer Epidemiology in Copenhagen, Denmark, and colleagues.
“HPV is an even better predictor in older women with a lower background HPV prevalence.” Of 10,758 women aged 20 to 29 years who were followed for two years for development of cervical cytological abnormalities, 370 women had findings on second examination, including 40 with atypical squamous cells of undetermined significance, 165 with low-grade and 165 with high-grade squamous intraepithelial lesions.
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!