In patients with age-related macular degeneration (AMD), depression accelerates decline in visual function, according to the results of a prospective, longitudinal analysis conducted at Wills Eye Hospital in Philadelphia.
Dr. Barry W. Rovner and associates evaluated 51 patients with preexisting AMD in one eye who lost vision in the second eye due to exudative AMD within the 6 weeks prior to baseline.
As a result, visual acuity in both eyes was worse than 20/70, the investigators report in the Archives of Ophthalmology for August. At baseline, 17 patients were depressed according to scores on the Center for Epidemiological Studies-Depression (CES-D) Scale. Six months later, the investigators re-evaluated 40 subjects.
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