Laurie Barclay, MD Aug. 21, 2002
Infants exposed to repeated painful stimuli, such as heel sticks, in the first 24 to 36 hours of life exhibit more intense pain responses during subsequent venipuncture, according to results of a prospective cohort trial reported in the Aug. 21 issue of The Journal of the American Medical Association.
To avoid the development of anticipatory pain and hyperalgesia, the investigators recommend closer attention to pain management for neonates. “This was the first study to look at anticipatory pain responses in newborns,” lead author Anna Taddio, PhD, from The Hospital for Sick Children in Toronto, Ontario, Canada, says in a news release. “This research confirmed anecdotal reports that infants become hypersensitive to pain and learn to anticipate pain as a result of cumulative exposures to pain.”
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