המידע באדיבות מדיקונטקסט
Last Updated: 2001-07-10 16:56:21 EDT (Reuters Health)
WESTPORT, CT (Reuters Health) – Tasks requiring immediate and sustained attention are compromised during migraine headaches, investigators in Houston, Texas report.
Dr. John Stirling Meyer, of the Veteran's Administration Medical Center, and associates administered Mini-Mental Status Examination, Cognitive Capacity Screening Examination, and Hamilton Depression Rating Scale tests to 49 patients. The subjects took the tests during a headache episode and again when they were headache free.
During headache episodes, subjects showed significant impairments in higher cortical function, attention, orientation, and other measures of cognitive function, the researchers report in the current issue of Headache Quarterly.
Women showed more cognitive declines during headaches than did men. Scores did not differ significantly between the 21 subjects with aura and the 28 without.
"This observation suggests that cognitive impairments are not significantly related to the two migraine types," investigators point out. Therefore, "aura-related spreading depression cannot account for the major pathogenesis responsible for temporary cognitive impairments."
Dr. Meyer's group speculates that the impairments are due to intermittent brain dysfunction, such as changes in cerebral blood flow, metabolic abnormalities, changes in electroencephalographic potentials and abnormalities in the serotonergic system.
Headache Q 2001;12:21-26.
-Westport Newsroom 203 319 2700
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