– The targets being set for treatment of diabetes in a new National Service Framework for Britain’s National Health Service are impractical for routine clinical care, an article in the June 29th issue of the British Medical Journal argues.
Dr. Peter H. Winocour of Queen Elizabeth II Hospital in Garden City, Hertfordshire, UK, says that aggressive targets for managing glycaemia, cholesterol, blood pressure and antiplatelet medication have only been attainable in 50% to 70% of participants in well-controlled studies, meaning that even fewer could be expected to achieve them in routine practice.
In his article, Dr. Winocour discusses guidelines for control of diabetes-related risk factors and concludes that “polypharmacy may be unavoidable.
Given the cardiovascular risk profile of type 2 diabetes, up to 10% of patients could require two of three hypoglycaemic agents (ultimately including insulin), at least three antihypertensive agents, two hypolipidaemic agents, and aspirin,” he writes. “A high proportion will also require treatment for coexistent cardiovascular disease and coincidental unrelated chronic disease. It is difficult to see how we can realistically expect patients to comply for long with such a draconian regimen requiring so many separate drugs.”
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!