The combination of calcipotriene and betamethasone dipropionate for treatment of psoriasis is faster and more effective than using either medication alone, say researchers.
Both treatments act differently in the management of psoriasis, but there was some uncertainty regarding the risks and benefits from their combined use. Consequently, researchers at Probity Medical Research in Waterloo, Ontario, Canada, designed a new vehicle to establish optimal stability of combined calcipotriene 50microg/g and bethametasone dipropionate 0.5mg/g. A total of 1,028 patients with psoriasis vulgaris were selected as participants in an international, multi-centre, prospective, randomised, double-blind parallel group for a four-week study. All had proven responsive to topical therapy.
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