Despite risks, stenting of vertebrobasilar stenosis can yield benefits

By Martha Kerr

SAN ANTONIO, Texas (Reuters Health) – Attendees at the American Stroke Association's 27th International Stroke Conference here heard that stent-assisted angioplasty of atherosclerotic intracranial vertebrobasilar arteries is feasible and can alleviate symptoms for at least 2 years–but the procedure is risky.

Investigators at the Cleveland Clinic Foundation described how they are using the newer, smaller stents developed for coronary arteries intracranially, to open occluded vertebrobasilar arteries.

After 2 years of follow-up, Dr. Peter A. Rasmussen announced that there have been no cases of in-stent restenosis in the 25 surviving patients of the original 29 patients who presented with transient ischemic attacks that had not responded to maximal anticoagulant or antiplatelet therapy. Also, 24 of the 25 remain asymptomatic, while one has episodes of double vision.

Dr. Rasmussen reported that 2 patients died as a result of procedural complications and two died from other causes during follow-up. Neurological complications developed in 6 patients.

Dr. Rasmussen concluded that intracranial stent placement is technically feasible but it is a high-risk procedure. If successful, it relieves symptoms in this group that has a 33% stroke risk within two years.

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