02/28/2002
By Veronica Rose
Developing imaging and embolization techniques may contribute to reducing the recurrence rate of juvenile nasopharyngeal angiofibroma, say Swedish researchers.
Surgeons from the Departments of Otorhinolaryngology and Surgery at Sahlgrenska University in Gothenburg designed a treatment and follow-up study of the long-term results in preoperative embolized and non-embolized patients.
Participants included 32 patients with juvenile nasopharyngeal angiofibroma who were treated between 1974 and 1998. Surgery had been performed on the majority either via an antral approach or with a lateral rhinotomy. During the 1970s, surgery had been combined with ligature of the external carotid artery. Since 1981, it has been combined with preoperative embolization.
Radiotherapy (45 Gy) was given to two patients as primary treatment, and three cases of multiple recurrence received radiotherapy (30-45 Gy) as secondary treatment. No recurrence was seen in patients who had received radiotherapy. The overall recurrence rate was 25 percent, with a recurrence rate of eight percent in patients who were not embolized and 41 percent among those who were embolized….
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