In nearly 20% of melanoma patients with multiple sentinel lymph nodes (SLN) evident on radioisotope and blue dye mapping, the node with the highest isotope count does not contain metastases, results of a new study indicate.
Based on this finding, “all blue-stained nodes as well as nodes that contain at least 10% of the isotope count of the hottest node should be harvested to detect nodal metastases,” lead author Dr. Ira A. Jacobs, from the University of Illinois at Chicago, told Reuters Health.
“We decided to study this topic because there was no good literature on which nodes should be removed” during SLN biopsy in patients with melanoma, Dr. Jacobs noted.




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