A retrospective autopsy study described in the September issue of the Journal of Pediatrics showed that 10% of infants with sudden unexpected infant death (SUID) had heart disease, that most of these were structural malformations, and that many were not identified before death.
“We found that heart disease is present in a significant percentage of autopsies of infants dying suddenly and unexpectedly,” write Adrian Dancea, MD, and colleagues from the University of Montreal in Quebec, Canada. “Anatomic malformations predominate; however, nonstructural heart disease is frequent and generally unrecognized before autopsy.” This retrospective study analyzed all autopsies in Quebec between January 1987 and December 1999 on infants with sudden death at age seven days to two years.
Cardiac pathology was present in 82 (9.7%) of 848 cases, and included a structural malformation in 54% of cases. The most common autopsy diagnosis was primary endocardial fibroelastosis, and other conditions included myocarditis, cardiomyopathy, tumors, septal defects, left ventricular hypoplasia, outflow obstruction, cyanotic heart disease, and vascular abnormalities.
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