NEW YORK (Reuters Health) Aug 20 –
In asthmatic patients, use of a leukotriene receptor antagonist (LTRA) protects against an almost doubling of the bronchial provocation dose required to produce a 20% fall in FEV1, according to a report in the July issue of Chest.
“Bronchial hyperresponsiveness or hyperreactivity is a noninvasive surrogate marker of airway inflammation, and is a reproducible method of assessing the efficacy of antiasthma therapy in the laboratory,” Dr. Brian J. Lipworth and Dr, Graeme P. Currie from the University of Dundee, Scotland, note.




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