Mild-to-moderate heart failure frequently complicates ST-segment elevation acute myocardial infarction (MI), and approximately doubles the risk of death or repeat MI within the following month, new study findings suggest.
Dr. David R. Holmes, Jr., of the Mayo Clinic in Rochester, Minnesota, and associates analyzed data from four international fibrinolytic therapy trials. They report in the January issue of the American Heart Journal that mild-to-moderate heart failure was documented for 17,949 (29.4%) of patients enrolled in the trials, after excluding those who had cardiogenic shock or whose heart failure status was unknown. Among these patients, heart failure was at baseline only in 8.7%, after admission in 57.6%, and at baseline and after in 33.7%.
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