NSAID Use For Treatment of Osteoarthritis Has Declined in US

– The use of nonsteroidal antiinflammatory drugs (NSAIDs) for the treatment of osteoarthritis (OA) declined from 1989 to 1998, and the use of safer medications became more frequent during this period.

 However, variations in use patterns, and the limited use of acetaminophen, suggest a more comprehensive response is required to optimize OA therapy. Dr. Randall S. Stafford, of the Stanford Center for Research in Disease Prevention, Palo Alto, California, and colleagues used data from the National Ambulatory Medical Care Survey to examine national trends in NSAID and acetaminophen use for the treatment of OA. They assessed 4471 visits of OA patients who were 45 years of age or older.

Treatment with NSAIDs, acetaminophen, or both for OA “steadily decreased from 49% of visits (1989 to 1991) to 46% (1992 to 1994) to 40% (1995 to 1998) (p = 0.001),” the team reports in the May issue of the Journal of Rheumatology. “Reduced NSAID use over this time period…was partially offset by a modest increase in acetaminophen use (5% to 10%; p = 0.001).”

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