Topical immunotherapy with diphenylcyclopropenone is an effective treatment for recalcitrant palmoplantar and periungual warts.
It should be considered as first-line treatment because of its high response rate, absence of scarring and painless application, according to investigators from the University of Alberta in Edmonton, Alberta, Canada.
The researchers evaluated diphenylcyclopropenone in a seven-year retrospective review during which 90 male and 121 female patients were sensitized. The patients were between five and 78 years old, and completed an average of five treatments over a six-month period.
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