05/27/2002 By Veronica Rose
Vegetarians have considerably higher levels of total plasma homocysteine, greater prevalence of hyperhomocysteinemia and lower levels of serum vitamin B12 than do non-vegetarians, say Italian researchers.
Clinicians from several Veronese Research Units designed a comparative study of fasting total plasma homocysteine (tHcy) levels in vegans, lacto-ovovegetarians and control subjects.
In addition, they evaluated the relationship between these levels and nutritional variables in vegetarians. Participants included 45 vegetarians with an average age of 46 years, composed of 31 vegans, (19 males, 12 females) and 14 lacto-ovovegetarians (six males, eight
females).
They were compared with 29 control subjects composed of 19 males and 10 females. High performance liquid chromatography was used to evaluate the total plasma homocysteine. Analysis of serum vitamin B12 and folate was undertaken by automated chemiluminescence systems. The clinical records for all vegetarians, together with their nutritional and
anthropometric variables were also collected.
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