NEW YORK (Reuters Health) Apr 30 – Osteoporosis and related factors explain much of the association between daily alendronate use and gastroduodenal perforation, ulcer, or bleeding, study findings published in the April 22nd issue of the Archives of Internal Medicine suggest.
"Isolated case reports of gastric ulcers after alendronate sodium use raised concern about the gastroduodenal safety of daily alendronate," Dr. K. Arnold Chan, of Brigham and Women's Hospital, Boston, and colleagues note.
…To investigate further, they compared 6432 patients
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