Laurie Barclay, MD
NEW YORK (MedscapeWire) May 01 Consensus guidelines for management of abnormal Papanicolaou (Pap) smears, developed at a conference sponsored by the American Society for Colposcopy and Cervical Pathology (ASCCP) on September 6-8, 2001, in Bethesda, Maryland, are summarized in the April 24 issue of The Journal of the American Medical Association.
"Women with atypical squamous cells (ASC) of undetermined significance (ASC-US) should be managed using a program of 2 repeat cytology tests, immediate colposcopy, or DNA testing for high-risk types of human papillomavirus (HPV)," write Thomas C. Wright Jr, MD, from Columbia University in New York, and colleagues. "Testing for HPV DNA is the preferred approach when liquid-based cytology is used for screening."
A panel of 121 experts in the diagnosis and management of cervical cancer precursors developed these guidelines using a multistep approach, including literature review and input from the professional community. They concluded that HPV testing has been clinically validated and can become integral to both screening and clinical management.
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