Implantable microsensors may revolutionize cardiac patient followup

מתוך medicontext.co.il
By Megan Rauscher

NEW YORK (Reuters Health) – In the near future, implanted microsensors will make it much easier to monitor the status of patients with congestive heart failure and abdominal aortic aneurysm.

That is according to Dr. Jay Yadav, of the Cleveland Clinic Foundation, who presented an update on the technology, known as micro-electro-mechanical systems (MEMS), during the 14th Annual International Symposium on Endovascular Therapy in Miami Beach, Florida.

In a telephone interview with Reuters Health, Dr. Yadav said: "This technology allows us to get real-time information on internal disease states, which we really can't do right now except when patients are in the hospital. For patients with heart failure, we can put a catheter in and get pressure measurements from inside the heart. For the abdominal aortic aneurysm population, we really have no way of measuring sac pressure after a stent-graft has been put in."

The wireless MEMS device is made of flexible plastic, is paper-thin, is about the size of a dime and requires no battery. It is powered by a hand-held transmitter/receiver.

Dr. Yadav said he his pleased with results in animal studies to date. "The key milestone–which is, can you actually detect aortic pressure from inside the body wirelessly without a battery using an antenna?–has been met." Human trials of the device in patients with abdominal aortic aneurysm are set to begin this spring.

In a case of abdominal aortic aneurysm, the device is inserted into the excluded portion of the aneurysm sac during the deployment of the endovascular stent-graft. It would alert the physician to "an unanticipated increase in fluid pressure that may be indicative of the late emergence of a Type II endo-leak," Dr. Yadav told conference participants.

For the heart failure patient, the device would be advanced via a catheter to the right heart vein. "With heart failure, the rationale is that if we can pick up increases in right heart pressure before the patient really decompensates, we can adjust their medication over the phone, and they don't have to be hospitalized," he told Reuters Health.

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