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Beneficial effects of exercise on osteoarthritis wane over time

מתוך medicontext.co.il

WESTPORT, CT (Reuters Health) – Exercise benefits patients with osteoarthritis (OA) of the knee or hip, but the effects decline over time and eventually disappear, according to a report in the December issue of the Annals of Rheumatic Diseases.

In a randomized, single blind study, Dr. M. E. van Baar, of the Netherlands Institute of Primary Health Care, Utrecht, and colleagues examined whether the effects of an exercise program in patients with OA of the knee or hip are sustained at 6 and 9 months.

The team compared two intervention groups. Patients in both groups received treatment from their general practitioners, "including patient education and drug treatment if necessary." In addition, the intervention group received exercise treatment from a physiotherapist for 12 weeks. Participants were followed for an additional 24 weeks.

Of 201 patients included in the study, 99 were randomized to exercise therapy and 102 patients were randomized to the control treatment. One hundred eighty-three patients completed the trial.

Exercise-treated patients visited their general practitioners a mean of 1.6 times in the 12-week treatment period, compared with 1.8 times for control patients (p = 0.03). Drugs were prescribed for 54% and 66% of the patients, respectively (p > 0.05).

"At 24 weeks exercise treatment was associated with a small to moderate affect on pain during the past week (difference in change between the two groups -11.5)," the authors report. By 36 weeks, however, they observed no differences between the groups.

"Future research should focus on finding ways of optimally maintaining beneficial effects over time," Dr. van Baar and colleagues conclude. "Important issues are optimal content and timing of treatment and compliance of the patient with exercise therapy."

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