Stress may affect fertility treatment success rate

מתוך medicontext.co.il

WESTPORT, CT (Reuters Health) – The success of infertility treatments may depend on minimizing the worries and fears of women who undergo these procedures, according to the results of a new study in the October issue of Fertility and Sterility.

Women who were optimistic that the treatment would work were more likely to give birth. In fact, women with the highest levels of stress were 93% less likely to deliver an infant by the end of the 5-year study compared with their more relaxed peers.

"This research determined that success rates for in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT) may, in part, be related to psychological stress," lead investigator Dr. Hillary Klonoff-Cohen, of the University of California, San Diego, said in an interview. "Clinicians could play an important role in counseling couples about stress reduction and providing access to support groups and educational materials."

In the study, 151 women between the ages of 26 and 49 years old answered questions about their moods, feelings of optimism, social support and methods of coping during their first visit to a fertility clinic and again just before undergoing treatment. The women underwent IVF or GIFT.

Women who reported the highest stress levels at the outset had fewer eggs retrieved and fertilized, compared with women who expressed optimism that they would become pregnant. Stressed women also had fewer embryos transferred into their wombs, the researchers report.

Women who reported feeling angry, hostile or depressed had fewer eggs to fertilize and fewer embryos to transfer.

The infants of women who felt "guilty" for considering stopping fertility treatment had infants with lower average birth weights and women who said that they "would do anything for a child" were five times more likely to have a multiple birth.

While stress showed negative effects in this study, the findings can also be seen in a positive light since optimism was linked with greater success, according to Dr. Michael Soules, president of the American Society for Reproductive Medicine.

"This is encouraging; a positive attitude to life and treatment can really make a difference," he said in a statement.

Exactly how stress affects the likelihood that a woman becomes pregnant with fertility treatments remains unclear, Dr. Klonoff-Cohen said. She added that the quality of a woman's eggs, as well as the quantity, plays a role in the ultimate success of the treatment.

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