Adequate blood pressure control is possible with antihypertensive therapy and aggressive follow up, even in an extremely challenging population of hypertensive patients.
That is the conclusion of a report from the African American Study of Kidney Disease and Hypertension.
This ongoing clinical trial seeks to evaluate the effect of blood pressure and choice of antihypertensive drug on the rate of renal function decline in a patient population for whom blood pressure control historically has been difficult to achieve.
The study included 1,094 hypertensive African-American patients in the United States (aged 18 to 70 years) who had glomerular filtration rates between 20 and 65 mL/min per 1.73 square meter, and no other identified cause of renal insufficiency. The patients were randomized to two groups.
One group had the goal to achieve the usual mean arterial blood pressure of 102 to 107 mm Hg. The other group’s goal was to achieve a mean arterial blood pressure of 92 mm Hg or lower.
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