מתוך medicontext.co.il
By Joene Hendry
WESTPORT, CT (Reuters Health) – The number of lifetime seizures may influence the age at which an epileptic woman begins menopause, the results of a small study suggest.
In a study of 31 middle-aged women with epilepsy, researchers found that those who went through early menopause–between the ages of 37 and 45 years–had more frequent lifetime seizures compared with women who went through menopause in their 50s.
"Seizure control may play an important role in reproductive health," the study's lead author, Dr. Cynthia L. Harden of Weill Medical College of Cornell University in New York, told Reuters Health.
She presented the findings on Wednesday at the American Epilepsy Society meeting in Philadelphia, Pennsylvania.
Dr. Harden's team found that among the 16 epileptic women who went through early menopause, all had at least 20 seizures during their lives, and 9 reported having more than 1 seizure per month. In contrast, 5 of the 15 who went through menopause in their 50s had fewer than 20 lifetime seizures. Only 6 had more than 1 seizure per month.
"Since the brain structures involved in normal reproductive functions can be affected by seizures…it made sense that high seizure rates might contribute to earlier than normal menopause," Dr. Harden explained in an interview.
The investigators found no evidence, however, that the number of antiepileptic medications that women received influenced age at menopause.
Dr. Harden said these findings may provide another reason to aggressively control epileptic seizures, since menopause is associated with an increased risk of heart disease and bone loss.
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